Migraine headaches are moderate to severe headaches that can cause pulsing or intense throbbing sensations in the head and are often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. It is estimated that 35 million Americans suffer from migraines resulting in significant economic loss to employers because migraine attacks can last for hours to days. Often patients have to find a dark quiet place to lie down as they are battling the symptoms of a migraine including the very debilitating feeling of nausea. The migraine market has been valued at around $4 billion dollars in the US and physicians often treat their patients with medications such as analgesics and triptans. Although these medications are first line therapy, there are millions of people who are under treated because they are having a difficult time finding relief from the migraine related nausea and vomiting.
Charleston Laboratories, Inc is dedicated to developing novel triptans and opioid analgesics for the acute treatment of migraine attacks without Migraine Induced Nausea and Vomiting (MINV).